Trending
- AI’s Dual Capacity and a Strategic Opportunity for African Peace and Security
- How African economies dealt with the 2025 debt maturity wall
- Africa’s Green Economy Summit 2026 readies pipeline of investment-ready green ventures
- East Africa banks on youth-led innovation to transform food systems sector
- The Washington Accords and Rwanda DRC Peace Deal
- Binance Junior, a crypto savings account targeting children and teens debuts in Africa
- African Union Agenda 2063 and the Conflicts Threatening “The Africa We Want”
- New HIV prevention drug is out — can ravaged African nations afford to miss it?
Browsing: WHO
mRNA-1644 utilizes Moderna’s messenger RNA (mRNA) technology to deliver a specific class of B cells needed to develop broadly neutralizing antibodies (bnAbs) to fight HIV infection. Inducing bnAbs is considered the primary goal of an HIV vaccine, and this requires B-cell activation.
The primary trial endpoints are safety and immunogenicity. The IAVI-sponsored clinical trial, IAVI G003, will test the safety and efficacy of vaccination with the HIV immunogen eOD-GT8 60mer, delivered via Moderna’s mRNA platform. eOD-GT8 60mer was developed by IAVI and Scripps Research teams and was initially tested in phase 1 clinical trial IAVI G001.
According to Contagion Live, IAVI G003 is expected to enroll 18 healthy, HIV-negative adults. The participants will receive 2 doses of eOD-GT8 60mer mRNA, which contains a portion of the viral sequence but cannot cause HIV infection. They will be monitored for safety for 6 months after their second dose, and their immune responses will be examined in molecular detail to evaluate whether the target was achieved.
Stavros Nicolaou, a Senior Executive at Aspen Pharmacare Group said in the absence of orders or commitments, Aspen is considering the repurposing of two COVID-19 production lines for the manufacture of other products.
“The continent would lose its only existing COVID vaccine manufacturing capacity, It would be a massive setback for Africa’s plans to localize and reduce its dependency on imported vaccines,” he said.
John Nkengasong, director of the Africa Centres for Disease Control and Prevention, said global health security would be undermined if companies like Aspen were not backed.
A sense of well-being encompasses a wide range of factors, including access to education and employment, as well as the…
Africa’s death rates from COVID-19 infections are significantly higher in patients with diabetes The disease causes inflammation and poor blood…
On Sunday, May 10th, statistics from the WorldOmeter showed that New York state had recorded 41 fatalities in 24 hours,…
According to the Tanzanian Ministry of Health, All 27 people who came in contact with the first patients tested negative…
Infections in Africa have been steadily rising after initial indications had shown the continent was not affected by Coronavirus compared…
It is now a fact that the coronavirus (COVID-19) outbreak is a pandemic according to World Health Organization (WHO), and…
Economists define a recession as a subdued growth that lasts at least six months and goes for another 18 months…
The world is on its heels as the coronavirus (COVID-19) has taken superpowers and developing nations hostage, limiting aerial movements,…